After serving prison time for a self-defense killing, Sailor Ripley reunites with girlfriend Lula Fortune. Lula's mother, Marietta, desperate to keep them apart, hires a hitman to kill Sailor. But he finds a whole new set of troubles when he and Bobby Peru, an old buddy who's also out to get Sailor, try to rob a store. When Sailor lands in jail yet again, the young lovers appear further than ever from the shared life they covet.
A large spider from the jungles of South America is accidentally transported in a crate with a dead body to America where it mates with a local spider. Soon after, the residents of a small California town disappear as the result of spider bites from the deadly spider offspring. It's up to a couple of doctors with the help of an insect exterminator to annihilate these eight legged freaks.
Una specie di ragni molto velenosi, importata erroneamente dal Venezuela, prolificherà molto rapidamente e si insinuerà in una tranquilla casa di provincia. Gli inquilini, insieme a tutta la cittadina, sono ignari di ciò che li aspetta...